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EU-RESPONSE

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Project NameEuropean Research and Preparedness Network for Pandemics and Emerging Infectious Diseases

Poject Acronym: EU-RESPONSE

Project Number101015736

Project Start Date: 01/07/2020

Project End Date30/06/2025

Project Summary: The overall objective of this proposal is to build a multinational, adaptive pan-European COVID-19 and emerging infectious diseases platform trial network, based on existing initiatives, experiences and competencies. 

Coordinator: Institut National de la Santé et de la Recherche Médicale (Inserm)

Objetives:

  • To expand, in the short-term, DisCoVeRy involving as many EU Member States and Associated Countries 
  • To build a multinational, European multi-arm COVID-19 platform trial beyond DisCoVeRy;
  • To provide in the mid-term a modular trial framework within this platform enabling most if not all European hospitals to participate at their preferred level of commitment;
  • To develop a network of hospitals with ICU and non-ICU departments within EU Member States and Associated Countries;
  • To build a strong governance for the selection of treatment and strategies to be evaluated, taking into consideration all stakeholders involved;
  • To develop a second-generation master protocol targeting in particular COVID-19;
  • To launch and conduct, in the medium term, through this platform a first trial based on an open call;
  • To coordinate the activities between different pan-European COVID-19 Adaptive Platform trials, establishing a single coordination mechanism with a coordinated strategy aligned with European and national policies.

Results:

  • Extending DisCoVeRy in Europe;
  • DisCoVeRy for Solidarity: a platform trial for COVID-19 and other emerging infectious diseases;
  • Coordination of the pan-European COVID-19 Adaptive Platform trials.

Costs:

Total Cost:  16,055,304.10 €
Budget of Centro Hospitalar Universitário São João for the project:  89,307.00 €

Project Website

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